International Technologist in Cytogenetics ASCP Practice Test

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What is the main focus of studying Q-banding?

Detecting deletions

Identifying chromosome inversions

Identifying chromosomal polymorphisms

Studying Q-banding primarily focuses on identifying chromosomal polymorphisms. Q-banding involves staining chromosomes with a fluorescent dye, which highlights specific regions of the chromosomes that exhibit variations in banding patterns. These variations can indicate the presence of polymorphisms, which are genetic differences among individuals in a population, often related to inherited traits.

This method is particularly useful in cytogenetics for distinguishing individual chromosomes and for recognizing structural variations that may not be evident through other staining techniques. Q-banding shows distinct patterns that can help researchers and clinicians identify homologous chromosomes, making it easier to analyze genetic diversity and chromosomal structure in various populations or individual cases.

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Staining chromatids

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