What is a common characteristic feature of DiGeorge syndrome?

DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is characterized by a range of developmental and physical anomalies, one of the most prevalent of which is congenital heart defects. These defects can vary in type and severity and may include conditions such as tetralogy of Fallot, truncus arteriosus, and ventricular septal defects. The underlying genetic cause is a deletion on chromosome 22, which affects the development of critical structures during embryonic development, including the heart.

The presence of congenital heart defects in individuals with DiGeorge syndrome is a key diagnostic feature and often prompts further investigation into other associated anomalies, such as immune deficiencies and developmental delays. This triad of symptoms highlights the critical needs for ongoing medical management and monitoring in individuals affected by the syndrome.

In contrast, the other options provided are not recognized as common characteristics of DiGeorge syndrome. A unilobed kidney is not a hallmark feature of the condition. High blood pressure is not directly associated with DiGeorge syndrome, and while polydactyly may occur in various genetic syndromes, it is not a typical finding in DiGeorge syndrome. Understanding these features is important in identifying and managing the condition effectively.