What is essential to confirm the integrity of a new hypotonic solution batch?

To ensure the integrity of a new hypotonic solution batch, it is critical to compare its physical properties to existing lots. This process involves assessing factors such as osmolarity, pH, and clarity, which are fundamental characteristics that can indicate if the new batch is suitable for use. Any significant deviations from the established properties of previous batches could suggest the potential presence of impurities or inconsistencies in the solution, which may affect overall performance in cytogenetic analyses.

By comparing physical properties, technicians can detect any changes that could impact the hypotonicity required for proper cell swelling in cytogenetic specimens, which is crucial for accurate chromosome analysis. This step acts as a practical quality control measure to maintain the reliability of the cytogenetic testing process.

While testing for chemical composition and documenting supplier information are also important practices in quality assurance, they do not specifically address the immediate verification of the batch's physical characteristics, which directly affect its performance in cytogenetics.