Which location can be shown by C-band?

Prepare for the International Technologist in Cytogenetics ASCP exam with comprehensive flashcards and practice questions. Each question is accompanied by hints and explanations. Ace your test with confidence!

The correct choice pertains to the visualization of constitutive heterochromatin using C-banding techniques. C-banding is a cytogenetic staining method specifically designed to selectively stain the heterochromatin regions of chromosomes, particularly at the centromeres where this type of chromatin is typically concentrated.

Constitutive heterochromatin is highly repetitive DNA and is found at certain chromosomal locations such as the centromeres and on the short arms of acrocentric chromosomes. The C-band technique helps in identifying these areas since they appear darkly stained under a microscope, highlighting the structure and arrangement of the chromosomes.

In contrast, euchromatin, characterized by being more gene-rich and actively transcribed, does not exhibit the same staining properties as constitutive heterochromatin and therefore would not be effectively visualized using C-bands. While centromeres are indeed regions that can exhibit C-banding, the specificity of the method to constitutive heterochromatin makes the targeted identification unique to that context. Telomeres, located at chromosome ends, are typically not the focus of C-banding either, as they are mostly representative of another chromatin type not encompassing the trait of heterochromatin. Thus, the best

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